Infantile spasms (IS) has been described as a challenging epilepsy syndrome because its drug resistance and poor prognosis, which have given rise to a large burden on society and patients’ families. IS typically have an onset between 3 and 12 months of age with a peak incidence around 6-7 months [1].However, the patients were divided into three groups by age at onset of spasms [2]: early onset ( less than 3 months), classic onset (3 months and up to 12 months), and late onset (12 months and older), respectively.
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