The success of epilepsy surgery relies on the accurate localization and complete resection or disconnection of the epileptogenic zone (EZ) from surrounding brain tissue. The epileptogenic zone is defined as the minimum amount of cortex that must be resected to produce seizure freedom and is consequently an area that can only be identified retrospectively based on epilepsy surgery outcome [1]. In contrast, the seizure onset zone (SOZ) is defined as the area of cortex where the seizure is generated and can be detected using scalp or intracranial EEG.
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