Quality of life and correlating factors in children, adolescents with epilepsy, and their caregivers: A cross-sectional multicenter study from Germany

Epilepsy is a common, chronic neurological disease with a clinical hallmark of recurrent seizures that places a major burden on patients, their caregivers, and society [1–3]. Moreover, disease-specific restrictions on self-sufficiency, mobility, career choice, family planning, and other social aspects as well as frequent epilepsy-related accidents and injuries have been shown to be associated with a reduced quality of life (QoL) and increased depression scores [4–7]. QoL is a complex and multidimensional construct representing the general “well-being” of individuals by outlining individual negative and positive aspects of life.

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