Plasma concentration and clinical effects of perampanel – the Kork experience

Therapeutic drug monitoring (TDM) is an established method to improve the quality of antiepileptic drug (AED) therapy. Especially with traditional AEDs such as carbamazepine, phenytoin, or ethosuximide, therapeutic ranges were defined and are still widely used. On the other hand, clinically reliable and useful ranges are still not defined for many new agents, including perampanel (PER) [1].

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