Efficacy of levetiracetam for reducing rolandic discharges in comparison with carbamazepine and valproate sodium in rolandic epilepsy

Rolandic epilepsy (RE) usually presents with infrequent seizures and has excellent prognosis presenting with characteristic abnormal discharges on electroencephalogram (EEG), mainly “rolandic discharges (RDs)” [1]. The most striking finding of RD is the significant increase in frequency during drowsiness and through all sleep stages. Several studies have provided the clear evidence that children with RE display a profile of pervasive cognitive difficulties and behavioral disturbances, and thus RE is not always benign disorder [2,3].