Long-term seizure outcome in pediatric patients with focal cortical dysplasia undergoing tailored and standard surgical resections

Focal cortical dysplasia (FCD) is a subgroup of cortical malformations characterized by abnormal regional neuronal migration and differentiation that result in aberrant cortical organization. [1] It is the most common anatomo-pathological feature in patients undergoing epilepsy surgery in childhood [2]. Prevalence figures have been rising over recent years due to improved MRI quality, but, even with the best methodology currently available, the sensitivity and specificity of imaging findings are limited and a diagnosis of FCD requires histological confirmation.