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Convulsive status epilepticus (SE) is a common neurological emergency that disproportionately affects young children and older adults [1–3]. SE is associated with a mortality of approximately 0-3% in children [1,4–7], 20-30% in older adults [7–9], and survivors often have neurological and cognitive deficits. Although these outcomes have been attributed to convulsive SE itself, etiology is a primary predictor of long-term outcome. The pathophysiological changes underlying SE are only partially understood [10,11], but an evaluation of the underlying pathophysiology may help optimize treatment strategies.