Neurology specialists’ visual interpretation of psychogenic nonepileptic seizures: contemplating their etiology and existing challenges

Psychogenic nonepileptic seizures (PNES) are manifestations of a complex disorder described by episodic changes in patient arousal, perception, movement and behavior [1,2]. PNES represent a vast and heterogeneous group of paroxysmal symptoms and events that look similar to epileptic seizures but cannot be explained by abnormal epileptiform activity. The distinction between epileptic seizures and PNES has become one of the points in recent discussions surrounding the use of the phrase “psychogenic nonepileptic seizures” itself [2–6].

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Changes in the patient call volume and call characteristics to an epileptologist during the COVID-19 pandemic

COVID-19 (coronavirus disease 2019) is the infectious respiratory disease caused by SARS-COV 2 virus (Severe Acute Respiratory Syndrome coronavirus 2). The World Health Organization (WHO) declared COVID-19 a pandemic on March 11th,2020 (Cuciotta and Vanelli, 2020). In New York hospitals introduced drastic changes to manage the surge of COVID-19 patients. Most outpatient clinics were canceled. Rapid adoption of telemedicine allowed continuity of care of existing patients while protecting health healthcare workers from infection.

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Seizure is a rare presenting manifestation of COVID-19

Since late 2019, the world has been experiencing a catastrophic pandemic of the coronavirus disease (COVID-19) that is caused by SARS-CoV2 [1] While seizures have not been frequently reported during the COVID-19 pandemic [2], affected patients may have hypoxia, multiorgan failure, and severe metabolic and electrolyte derangements [1]; hence, it is plausible to expect acute symptomatic seizures to happen in these patients. In addition, most coronaviruses share a similar viral structure and infection pathway; a growing body of evidence indicates ...

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Measuring the effects of pre-test probability on out-patient first EEG investigation in children – a guide to evidence-based EEG triage in a pandemic

Optimum management of children with suspected seizure disorders involves combination of a specialist child-neurology opinion and recording of an EEG1–3. Interictal epileptiform abnormalities (IEAs) occur in 30-64% of first-time EEGs in children with first unprovoked seizure or epilepsy presentations4–6 and are associated with higher rates of seizure recurrence7. Beyond estimation of recurrence risk, EEG can sometimes help to identify specific epilepsy syndromes, which can be particularly informative for the management and prognosis of some children1.

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Does glucose influence multidien cycles of interictal and/or ictal activities?

Studies of epilepsy surveillance systems, ictal and interictal epileptiform activities (IEA) show circadian and multidien patterns, with multiday patterns of rising phase IEA suggesting seizures are more likely [1–4]. IEA are non-ictal patterns that Responsive Neurostimulation Systems (RNS) may detect via surveillance EEG, patterns could include spikes, repeated sharp waves, polyspikes and fast oscillations [3,5]. Biomarker studies might clarify how RNS evident mulitidien IEA and ictal risk are related [4,6,7].

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The perceived impact of COVID-19 and associated restrictions on young people with epilepsy in the UK: young people and caregiver survey

The coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is having a profound effect on all societies. It has resulted in tens of millions of infections and over 1 million deaths worldwide (https://covid19.who.int/ accessed 19th October 2020). Countries have taken unprecedented steps to respond to the public health threat posed by the pandemic. In the UK the government imposed a range of restrictions in late March 2020 including a directive to stay at ...

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Impact of COVID-19 pandemic on epilepsy practice in India: A tripartite survey

The ongoing global Coronavirus Disease (COVID-19) pandemic, caused by a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has affected the health care including neurologic care world over. [1,2] In addition to the direct affection of nervous system by the SARS-CoV-2, the COVID-19 pandemic may have indirect impact on patients with non-COVID-19 diseases [3]. This indirect impact mainly results from the reluctance of the patients with non-COVID diseases to seek medical care because of the fear of contacting COVID-19 infection ...

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Personality changes in patients with refractory epilepsy after surgical treatment: a systematic review

Epilepsy is one of the most serious and common neurological diseases, affecting approximately 50 million people worldwide [1]. Epilepsy is known to be a potentially disabling, chronic, and socially isolating condition, especially in refractory cases. As a severe disease of the central nervous system, it can influence cognitive functions, affecting attention and memory [2,3]. But does epilepsy have an impact on patients’ personality? Personality is defined as the characteristic sets of behavior, cognition, and emotional patterns that develop from biological ...

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Sleep in Dravet syndrome: A parent-driven survey

Dravet syndrome was first described in 1978 as a rare form of epilepsy that generally presents in the first year of life [1]. While Dravet syndrome is often characterized as a seizure disorder, it is a multi-faceted early life developmental and epileptic encephalopathy (DEE) that impacts many areas of functioning. There are few systematic investigations that characterize these other features of Dravet syndrome.

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