Abstract
Objective
The relationship between sleep and epilepsy is important but imperfectly understood. We sought to understand the mechanisms that explain the differences in sleep homeostasis observed in children with epilepsy.
Methods
We used a neural mass model to replicate sleep electroencephalography (EEG) recorded from 15 children with focal lesional epilepsies and 16 healthy age-matched controls. Different parameter sets were recovered in the model for each subject.
Results
The model revealed that sleep EEG differences are driven by enhanced firing rates in the neuronal populations of ...
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