Abstract
Objective
Drug-resistant focal epilepsy is associated with abnormalities in the brain in both gray matter (GM) and superficial white matter (SWM). However, it is unknown if both types of abnormalities are important in supporting seizures. Here, we test if surgical removal of GM and/or SWM abnormalities relates to post-surgical seizure outcome in people with temporal lobe epilepsy (TLE).
Methods
We analyzed structural imaging data from 143 patients with TLE (pre-op diffusion magnetic resonance imaging and pre-op T1-weighted MRI) and 97 healthy controls. We ...
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