Abstract
Objective
To date, the identification of objective biomarkers of neural epileptic activity (EA) remains challenging. We therefore investigated whether neuronal complexity could serve as an interictal electroencephalographic measure of EA, independent of interictal epileptiform discharges (IEDs). By tapering anti-seizure medication (ASM) during video-EEG (electroencephalography) monitoring (VEM), we studied whether changes in neuronal complexity could reliably indicate the increase in EA and identify patients with epilepsy.
Methods
The study included 27 patients with unilateral mesial temporal lobe epilepsy (TLE) and 24 control patients with ...
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