Guideline conform initial monotherapy increases in patients with focal epilepsy: A population-based study on German health insurance data

Epilepsy is a common and chronic neurological disorder that imposes a substantial burden on individuals and society as a whole. The initial diagnosis of epilepsy is associated with costs of diagnostic procedures, inpatient admission and related loss of income [1,2]. Even after a first seizure or with newly established diagnosis of epilepsy, patients are affected by social stigma, reduced employment opportunities and impaired quality of life for themselves and their caregivers, resulting in increased indirect and intangible costs [3–8].

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