Biomarkers are widely used in translational research as well as in everyday medical practice in different scenarios, including epilepsy. However, so far, a consensus on their definition and application is lacking. The profound and mutually influencing connection between sleep and epilepsy is well known and interests different epileptic syndromes either of pediatric and adult age, as well as other non-epileptic but otherwise dreadful conditions like sudden unexpected death in epilepsy (SUDEP) [1].
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