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According to the hodotopic framework, execution of higher cognitive functions involves the interaction of multiple cortical regions via white matter fibers [1]. According to this concept, if the cortical regions that are responsible for higher cognitive functions are partially damaged, while the subcortical network is preserved, none or only transient symptoms may occur. When an epileptogenic zone (EZ) is located within the functionally dominant cortex, surgical resection is often avoided. However, we believe that these areas are resectable according to the hodotopic framework.