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Mesial temporal lobe epilepsy (mTLE) is the most common medically intractable but surgically remediable epilepsy in adults, with a characteristic seizure semiology and unilateral EEG onset. [1,2] The hippocampus is commonly regarded as the seizure focus in mTLE, with widespread cortical and subcortical regions involved. [3,4] As the most established therapeutic procedure for refractory mTLE, anterior temporal lobectomy (ATL) resects the hippocampus and adjacent mesial temporal structures, offering a favorable seizure-freedom rate of 60-70%.