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The principal source of energy for mammalian brains is glucose [1]. Neurons are among the cells that consume the most energy and rely on a steady supply of glucose [2]. Despite accounting for only 2% of total body weight, the human brain consumes 20% of all glucose-derived energy, making it the leading glucose consumer [3]. Glucose metabolism is indirectly involved in ATP generation which provides energy that is essential for fundamental neuronal processes [4]. Furthermore, glucose metabolism produces energy (ATP) and precursor material for neurotransmittersynthesis [5].