Neuropsychological profile and drug treatment response in Idiopathic Generalized Epilepsy

In adults, Idiopathic Generalized Epilepsies (IGE) comprise Juvenile Absence Epilepsy (JAE), Juvenile Myoclonic Epilepsy (JME) and Epilepsy with Generalized Tonic-Clonic Seizures Alone (GTCA) and are associated with worse social outcome as compared to normal population controls. [1,2] Although more than 90% finally achieve seizure control, only one third of the patients is “easy-to-treat” due to the inverse correlation of efficacy and side effects of the most widely used anti-seizure medication (ASM).

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