Circadian rhythm of blood pressure in patients with drug-resistant mesial temporal lobe epilepsy

Interictal autonomic dysfunction in patients with epilepsy (PWE) has been evaluated mainly at the cardiovascular level, with heart rate variability being the most studied parameter and alterations observed mainly in patients with temporal lobe epilepsy (TLE), Dravet syndrome and drug-resistant epilepsies [1]. Despite the fact that there have been some studies that have evaluated ictal and periictal blood pressure (BP) in PWE [2–4], interictal BP and the possible alteration of its central control have not been widely evaluated: the prevalence of hypertension in PWE is similar to that in the general population [5].

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