The role of neutrophil-to-lymphocyte ratio in predicting outcomes in patients with status epilepticus: considerations beyond CBC

We read with great interest the article “Admission neutrophil-to-lymphocyte ratio predicts length of hospitalization and need for ICU admission in adults with Status Epilepticus” by Olivo et al [1]. The objective of the study was to investigate the correlation between admission neutrophil-to-lymphocyte ratio (NLR) and hospitalization time, need for ICU admission, and 30-day mortality in patients with Status Epilepticus (SE), as a new, uncomplicated, and dependable marker of inflammation. The study identified that the optimal NLR cutoff point for predicting the need for ICU admission was 3.6, which had 90.5% sensitivity and 45.3% specificity (95% confidence interval, area under the curve: 0.678; p = 0.011; Youden’s index=0.358.

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