Longitudinal analysis of interictal electroencephalograms in patients with temporal lobe epilepsy with hippocampal sclerosis

Temporal lobe epilepsy (TLE) is the most common form of focal epilepsy in adults [1]. One of the main causes of TLE is hippocampal sclerosis (HS) [2]. TLE has a constellation of signs and symptoms, but the main criterion for diagnosis is the presence of characteristic seizure semiology [3]. The clinical definition of TLE with HS (TLE-HS) is based on electroencephalograms (EEGs), video EEGs, magnetic resonance imaging (MRI) findings, and neuropsychological tests [2].