Brains, Complex Systems and Therapeutic Opportunities in Epilepsy

The notion of epilepsy as a network disease is rapidly gaining traction, particularly in the domains of whole brain networks as measured with MRI, MEG and EEG[1]. This concept is illustrated by the growing recognition that lesional focal epilepsies are disorders that widely disrupt neural systems that are outside of the lesion, but which are part of a brain network that have capacity to generate seizures[2]. However, the network concept can be applied far more broadly than the level of the whole brain networks.

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