Seizure is a rare presenting manifestation of COVID-19

Since late 2019, the world has been experiencing a catastrophic pandemic of the coronavirus disease (COVID-19) that is caused by SARS-CoV2 [1] While seizures have not been frequently reported during the COVID-19 pandemic [2], affected patients may have hypoxia, multiorgan failure, and severe metabolic and electrolyte derangements [1]; hence, it is plausible to expect acute symptomatic seizures to happen in these patients. In addition, most coronaviruses share a similar viral structure and infection pathway; a growing body of evidence indicates that neurotropism is one common feature of coronaviruses [3].