Application of the APE2-CHN and RITE2-CHN scores for autoimmune seizures and epilepsy in Chinese patients: A retrospective study

Epilepsy is a debilitating neurological disorder characterized by seizures. Structural, metabolic, genetic or infectious factors are often identified as the cause of epilepsy, but in a substantial number of patients the etiology is unclear [1]. In the past few years, emerging data have revealed an autoimmune cause in patients with previous epilepsy with unknown etiology [2–6], and in the 2017 International League Against Epilepsy (ILAE) Classification, autoimmune epilepsy was recognized as a distinct etiological subgroup of epilepsy [1].