The relationship between olfaction, which is one of the chemosenses, and epilepsy has long been of interest to physicians. In the 19th century, olfactory dysfunction was observed in patients with temporal lobe epilepsy. Temporal lobe structures were therefore thought to have a role in olfactory function 1. Various studies since have revealed that the temporal lobe plays an important role in the perception of odors. In particular, the entorhinal cortex, the piriform cortex, and the amygdala are closely related to olfactory perception 2.
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