Abstract
Objective
We aimed to evaluate early-life epilepsy incidence, seizure types, severity, risk factors, and treatments among survivors of acute neonatal seizures.
Methods
Neonates with acute symptomatic seizures born 7/2015-3/2018 were prospectively enrolled at nine Neonatal Seizure Registry sites. One-hour EEG was recorded at age three months. Post-neonatal epilepsy and functional development (Warner Initial Developmental Evaluation of Adaptive and Functional Skills – WIDEA-FS) were assessed. Cox regression was used to assess epilepsy-free survival.
Results
Among 282 infants, 37 (13%) had post-neonatal epilepsy by 24-months [median age ...
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