Intracranial Evaluation and Laser Ablation for Epilepsy with Periventricular Nodular Heterotopia

The disruption of radial neuronal migration during brain development results in malformations composed of heterotopic grey matter (Barkovich et al., 2012). These may form continuous bands (laminar heterotopia) or discrete nodules, either in subcortical or periventricular locations (periventricular nodular heterotopia, PVNH). PVNH typically resides along the walls of the ventricular trigone, either unilaterally or bilaterally (Tassi et al., 2005). Nodular heterotopia is often associated with other types of cortical malformation, including polymicrogyria (PMG) (Wieck et al., 2005) and focal cortical ...

Seguir leyendo →
0

Guideline conform initial monotherapy increases in patients with focal epilepsy: A population-based study on German health insurance data

Epilepsy is a common and chronic neurological disorder that imposes a substantial burden on individuals and society as a whole. The initial diagnosis of epilepsy is associated with costs of diagnostic procedures, inpatient admission and related loss of income [1,2]. Even after a first seizure or with newly established diagnosis of epilepsy, patients are affected by social stigma, reduced employment opportunities and impaired quality of life for themselves and their caregivers, resulting in increased indirect and intangible costs [3–8].

Seguir leyendo →
0

Effects of Levetiracetam Monotherapy on Sperm Parameters and Sex Hormones: Data from Newly Diagnosed Epilepsy Patients

Epilepsy is one of the most common neurological diseases worldwide [1]. The disease has an impact on the reproductive system. Males with epilepsy have lower fertility rates, hypo-sexuality and reduced potency in the population [2,3]. Establishing a direct connection between reduced fertility and epilepsy has been difficult [4–6]. Although reduced potency and sperm abnormalities were reported in some studies, the etiology is thought to be multifactorial [10–12]. Thus, the effects of anti-epileptic drugs on sex hormones and the reproductive system ...

Seguir leyendo →
0

Stereo-EEG, radiofrequency thermocoagulation and neuropathological correlations in a patient with MRI-negative type IIb focal cortical dysplasia

Epilepsy surgery is particularly effective in patients with type II focal cortical dysplasia (FCD), with a seizure freedom rate of up to 85% [1] that is probably due to an overlap between the anatomical lesion and the Epileptogenic Zone (EZ). In some cases, when the EZ is not properly identified, an invasive stereo-electro-encephalography (SEEG) may be required. During SEEG recordings, radiofrequency thermocoagulation (RF-THC) can be performed since there is increasing evidence that it can be beneficial to treat focal epilepsy ...

Seguir leyendo →
0

Do demographic and socio-economic characteristics of women with epilepsy influence contact with joint obstetric/neurology services in Northern Ireland?

Epilepsy is the most common serious neurological disorder in the UK with an estimated prevalence of between 0.7 and 0.8% [1,2]. The incidence is about 0.05% (50 per 1,000,000 population) per year [2] with incidence rates peaking in childhood and older age. Approximately 23% of people with epilepsy are women of child bearing age [3]. A population based study estimated that 0.33% of pregnancies involve active maternal epilepsy [4].

Seguir leyendo →
0
Página 83 de 86 «...6070808182838485...»